Atrial fibrosis in atrial fibrillation pre-ablation assessed by CMR: impact in atrial size and function?

Methods 47 (42 male, 42±8 years-old) consecutive patients (pts) with paroxysmal AF and indication to ablation were included. Exclusion criteria for CMR: non-sinus rhythm and general contra-indications. Before ablation all underwent CMR for left atrial angiography for CARTO mapping. Using CMR, the following variables were assessed: left ventricle (LV) and left atrium (LA) volumes and ejection fraction (SSFP, short-axis), LV LGE was assessed as presence and amount (LGE mass/LV mass). LA LGE location was assigned to 3 atrial walls: anterior, posterior and septal. The extension was classified in 3 degrees, according to the number of atrial walls with LGE: 1=one wall, 2=two walls; 3=three walls. For CMR analysis dedicated software was used (Philips View Forum Release 6.1).